Tim De Meyer

Tim De Meyer is a Tenure Track Professor of the Bioinformatics Multidisciplinary Research Partnership N2N (From Nucleotides To Networks) at BioBix, Department of Mathematical Modelling, Statistics and Bioinformatics, with as main focus the data-analysis of high-throughput experiments and its application to successful aging research (particularly cardiovascular disease and cancer). After finishing his master’s degree in BioScience Engineering (2004) at Ghent University (FBE, UGent), and his PhD in 2008 at BioBix (same faculty), he was a postdoctoral fellow for IWT (2008-2009) and FWO (2009-2011), after which he was appointed as Tenure Track Professor. Aging is a complex phenomenon featured by both genetic and environmental components, and particularly the effects of their interactions. We study one type of these interactions, epigenetic modifications (sensu lato), and are more specifically interested in the roles of DNA-methylation, histone modifications, telomere biology and microRNAs in the aging process. Herefore, we apply high-throughput methodologies, with a special focus on novel technologies such as next-generation sequencing. This approach shifts the workload from bench to bioinformatics, requiring expertise in experimental design, statistical data-analysis, algorithm development and data mining. These topics are BioBix’s major strongholds, and are also used for other platforms such as NMR-based metabolomics and DNA-microarray analysis.

Although our research is not limited to cardiovascular aging and disease, one major interest is the Asklepios Study, a longitudinal population study focusing on the interplay between aging, cardiovascular haemodynamics and inflammation in (preclinical) cardiovascular disease, and the role of epigenetics in these processes. The skills of BioBix are also often used in the fields of crop protection and plant ecology.


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